OPPT_1,4-Dioxane_B. Ecological Toxicology

Project ID

2544

Category

OPPT REs

Added on

March 7, 2017, 3:18 p.m.

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Technical Report

Abstract  Environmental Engineering Laboratory Aquatic Toxicity Work Sheet. Product Environmental Data Aqueous Fluorochemical Emulsion. 96-hour Lc50 Aquatic Tests on Fathead Minnows. Product Environmental Data Aqueous Fluorochemical Emulsion. Product Environmental Data Aqueous Fluorochemical Emulsion. Product Environmental Data Aqueous Fluorochemical Emulsion. Product Environmental Data Fluorochemical Solution. Product Environmental Data Fluorochemical Solution Polymer. Product Environmental Data. Product Environmental Data Aqueous Fluorochemical Emulsion. In Vitro Microbiological Mutagenicity Assays of 3m Company Compounds T-2962coc and T-2963coc. In Vitro Microbiological Mutagenicity Assays of 3m Company Compound T-2228 Coc in Desiccators. In Vitro Microbiological Mutagenicity Assays of 3m Company Compound T-2227 Coc in Desiccators. Mutagenicity Evaluation of T-2002 Coc Final Report.

Technical Report

Abstract  Testing was conducted with the fathead minnow, Pimephales promelas Rafinesque, to estimate the acute and chronic toxicity of 1,4-dioxane to fishes. A static acute test with juvenile fathead minnow resulted in a 96-h LCSO of 13,000 mg/L; sublethal effects were noted at 10,000 mg/Land higher. The highest no observed effect level (NOEL) was 6,000 mg/L. The test substance in the static test was practically non-toxic to the fathead minnow, according to a categorization system used by the U.S. EPA. The chronicity of 1,4-dioxane was assessed by conducting a flow-through embryo-larval test. Fathead minnow embryos, less than 24 h ~ fertilization, were used to start the test. Fathead minnow embryos were exposed to mean analyzed concentrations of 27.6, 40.3, 65.3, 99.7, and 145 mg/L The test was terminated after 32 days of exposure. Statistical analysis of the data demonstrated no significant differences (p<0.05) in the number of embryos that hatched, day-to-mean hatch, number of deformed larvae, larval survival or larval weight at any test concentration. The MATC is greater than 145 mg/L.

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