OPPT_Trichloroethylene (TCE)_F. Human Health

Project ID

2585

Category

OPPT REs

Added on

March 8, 2017, 8:44 a.m.

Search the HERO reference database

Query Builder

Search query

56 items found. Displaying 25 items on page 1 of 3.

Book/Book Chapter

Effects of Trichloroethylene on Behavioral Performance Capabilities

Stewart RD et al. 1974

Abstract  Biochemical and toxicological study of the trichloroethylene-induced behavioral decrements in human beings. Data are given for acute 8-hour exposure to trichloroethylene (79016) vapor; subjective responses such as headache, nausea, dizziness, abdominal pain, chest pain, and eye, nose, and throat irritation; final analysis of variance for complex reaction time, tachistoscope perception, digit span test, finger dexterity, coordination test, and inspection test. In all six tests variability among subjects is found to be highly significant, suggesting the need for minimizing the effect of subject variation in such experiments. Trichloroethylene vapor concentration is found to be an insignificant source of variation in five of six tests

Technical Report

Health Hazard Evaluation Report No. HHE-73-151-141, Essex Wire Corporation, Kenton, Ohio

Bloom TF, Kramkowski, RS, and Cromer, JW 1974

Abstract  Trichloroethylene (79016) is cited as not toxic at the levels found near degreasers and a die cleaning operation in the winding area of a plant manufacturing ignition coils. The epoxy curing agent dodecyl-succinic-anhydride, used in the epoxy molding area is also considered to be present at levels which are not toxic. Based on medical interviews with workers, environmental exposure in the past to trichloroethylene and dodecyl-succinic-anhydride may have been at toxic concentrations.

Technical Report

Toxicological review of trichloroethylene (CAS No. 79-01-6) in support of summary Information on the Integrated Risk Information System (IRIS)

U.S. Environmental Protection Agency 2011

Abstract  There is substantial potential for human exposure to trichloroethylene (TCE), as it has a widespread presence in ambient air, indoor air, soil, and groundwater. At the same time, humans are likely to be exposed to a variety of compounds that are either metabolites of TCE or which have common metabolites or targets of toxicity. Once exposed, humans, as well as laboratory animal species, rapidly absorb TCE, which is then distributed to tissues via systemic circulation, extensively metabolized, and then excreted primarily in breath as unchanged TCE or carbon dioxide, or in urine as metabolites. The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to trichloroethylene. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of trichloroethylene

Technical Report

TSCA workplan chemical risk assessment for Trichloroethylene: Degreaser and arts/crafts uses (External Review Draft)

U.S. Environmental Protection Agency 2012

Abstract  The United States Environmental Protection Agency (U.S. EPA), Office of Pollution Prevention and Toxics (OPPT), identified and chose trichloroethylene (TCE) for risk evaluation as part of its Existing Chemicals Management Program under the Toxics Substances Control Act (TSCA). TCE is a volatile organic compound (VOC) that is classified as a human carcinogen.  Its consumption in the U.S. is 255 million pounds (lbs) per year. TCE is widely used in industrial and commercial processes, and also has some limited uses in consumer products. Main Conclusions of this Risk Assessment This risk assessment identifies cancer risk concerns and short‐term and long‐term non‐cancer risks for workers and occupational bystanders at small commercial degreasing facilities and dry cleaning facilities that use TCE‐based solvents and spotting agents, respectively. EPA/OPPT also identifies short‐term non‐cancer risks for consumers and residential bystanders from the use of TCE‐containing solvent degreasers and spray-applied protective coatings.

Filter Results
Project Tags