Maternal benzene exposure and low birth weight risk in the United States: a natural experiment in gasoline reformulation

Zahran, S; Weiler, S; Mielke, HW; Pena, AA

HERO ID

1063698

Reference Type

Journal Article

Year

2012

Language

English

PMID

22177084

HERO ID 1063698
In Press No
Year 2012
Title Maternal benzene exposure and low birth weight risk in the United States: a natural experiment in gasoline reformulation
Authors Zahran, S; Weiler, S; Mielke, HW; Pena, AA
Journal Environmental Research
Volume 112
Page Numbers 139-146
Abstract We investigate the relationship between maternal exposure to benzene and birth weight outcomes for resident births in the United States in 1996 and 1999, taking advantage of a natural experiment afforded by the regulation of benzene content of gasoline in various American cities. Regression results show that a unit increase (μg/m(3)) in maternal exposure to benzene reduces birth weight by 16.5 g (95% CI, 17.6 to 15.4). A unit increase in benzene exposure increases the odds of a low birth weight event by 7%. Similarly, a 1 μg/m(3) increase in benzene concentration increases the odds of very low birth weight event by a multiplicative factor of 1.23 (95% CI, 1.19 to 1.28). Difference-in-differences analyses show that birth weight increased by 13.7 g (95% CI, 10.7 to 16.8) and the risk of low birth weight decreased by a factor of .95 (95% CI, .93 to .98) in counties experiencing a 25% decline in benzene concentrations from 1996 to 1999. Public health policy and economic implications of results are discussed.
Doi 10.1016/j.envres.2011.11.008
Pmid 22177084
Wosid WOS:000299804800018
Url https://www.proquest.com/docview/1710232880?accountid=171501&bdid=64565&_bd=s3s8GK7586k3%2FY7uk8Uq0p86FtE%3D
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Benzene emissions; Benzene ambient concentration; Birth weight; Low birth weight
Is Qa No