Detection of explosives by olfactory sensory neurons
Corcelli, A; Lobasso, S; Lopalco, P; Dibattista, M; Araneda, R; Peterlin, Z; Firestein, S
HERO ID
1065715
Reference Type
Journal Article
Year
2010
Language
English
PMID
| HERO ID | 1065715 |
|---|---|
| In Press | No |
| Year | 2010 |
| Title | Detection of explosives by olfactory sensory neurons |
| Authors | Corcelli, A; Lobasso, S; Lopalco, P; Dibattista, M; Araneda, R; Peterlin, Z; Firestein, S |
| Journal | Journal of Hazardous Materials |
| Volume | 175 |
| Issue | 1-3 |
| Page Numbers | 1096-1100 |
| Abstract | The response of olfactory sensory neurons to TNT and RDX as well as to some volatile organic compounds present in the vapors of antipersonnel landmines has been studied both in the pig and in the rat. GC/MS analyses of different plastic components of six different kinds of landmines were performed in order to identify the components of the "perfume" of mines. Studies on rat olfactory mucosa were carried out with electro-olfactogram and calcium imaging techniques, while changes in the cyclic adenosine monophosphate (cAMP) levels following exposure to odorants and explosives were used as a criterion to evaluate the interaction of TNT and RDX with olfactory receptors in a preparation of isolated pig olfactory cilia. These studies indicate that chemical compounds associated with explosives and explosive devices can activate mammalian olfactory receptors. |
| Doi | 10.1016/j.jhazmat.2009.10.054 |
| Pmid | 19913995 |
| Wosid | WOS:000274490400142 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-72049117619&doi=10.1016%2fj.jhazmat.2009.10.054&partnerID=40&md5=9d6a65011c5b19cb0494c74077e68129 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Calcium imaging; Isolated cilia; Olfactory sensory neuron |
| Is Qa | No |