Munitions wastewater treatments: Does chlorination or ozonation of individual components produce microbial mutagens?
Simmon, VF; Eckford, SL; Griffin, AF; Spanggord, R; Newell, GW
HERO ID
1065738
Reference Type
Journal Article
Subtype
Abstract
Year
1977
Language
English
| HERO ID | 1065738 |
|---|---|
| Material Type | Abstract |
| In Press | No |
| Year | 1977 |
| Title | Munitions wastewater treatments: Does chlorination or ozonation of individual components produce microbial mutagens? |
| Authors | Simmon, VF; Eckford, SL; Griffin, AF; Spanggord, R; Newell, GW |
| Journal | Toxicology and Applied Pharmacology |
| Volume | 41 |
| Issue | 1 |
| Page Numbers | 197 |
| Abstract | A number of compounds present in wastewater from munitions plants were examined before an dafter ozonation of chlorination to dermine whether any were mutagenic before treatment and whether such activity was affected by the treatment. Several photolytic as well as metabolic products of trinitrotoluene (TNT) also were examined for mutagenic activity. Test materials included TNT, TNT production wastewater, and individual components of TNT wastewater (1,3-dinitrobenzene; 2,4-dinitrotoluene; 3,5-dinitrotoluene; hexahydro-1,3,5-trinitro-s-triazine (RDX); octahydro-1,3,5,7-tetranitro-s-tetrazine (HMX); components of photolysed TNT; pentaerythritol tetranitrate (PETN); and trinitroresorcinol. The in vitro mutagenic assays used were the Ames Salmonella/microsome assay (strains TA1535, TA1537, TA1538, TA98, and TA100) and mitotic recobination in the yeast, Saccharomyces cerevisiae D3. A metabolic activation system using the posmitochondrial supernatant fraction of liver from rats pretreated with Aroclor 1254 was included in each assay procedure. Materials found to be mutagenic prior to and after treatment were trinitrobenzene, trinitrobenzaldehyde, trinitrobenzonitrile, and 50 and 100% photolysed TNT wastewater. Neither ozonation nor chlorination significantly altered the mutagenic activity of the materials tested. |
| Wosid | WOS:A1977DR14000170 |
| Url | http://linkinghub.elsevier.com/retrieve/pii/0041008X7790062X |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: TOXICOL APPL PHARMACOL 41 ISSN: |
| Is Public | Yes |
| Language Text | English |
| Keyword | 118-96-7; 99-65-0; 121-14-2; 618-85-9; 121-82-4; 2691-41-0; 78-11-5; 82-71-3 |
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