Exposure to respirable flour dust and gliadin in wheat flour mills
Khodadadi, I; Abdi, M; Aliabadi, M; Mirmoeini, ES
| HERO ID | 1073844 |
|---|---|
| In Press | No |
| Year | 2011 |
| Title | Exposure to respirable flour dust and gliadin in wheat flour mills |
| Authors | Khodadadi, I; Abdi, M; Aliabadi, M; Mirmoeini, ES |
| Journal | Journal of Occupational Health |
| Volume | 53 |
| Issue | 6 |
| Page Numbers | 417-422 |
| Abstract | <strong>OBJECTIVES: </strong>The aim of this study was to determine the concentrations of respirable flour dusts and gliadin as well as gliadin-specific serum antibodies in exposed workers of Hamadan wheat flour mill factories.<br /><br /><strong>METHODS: </strong>Blood samples from 95 exposed workers and 80 air samples from flour packing, husk packing, flour production and wheat unloading areas were collected. Respirable flour dust density was measured by a gravimetric method, and dust gliadin concentration as well as serum antibodies were determined by enzyme-linked immunosorbent assays.<br /><br /><strong>RESULTS: </strong>The Time-weighted average (TWA) flour dust density was higher in all factories (1.56-4.68 mg/m(3)) compared with the threshold limit value (0.5 mg/m(3)) of ACGIH and showed a positive correlation with the gliadin concentration (p<0.05). Additionally, the respirable dust and gliadin concentrations were significantly higher at flour packing workstations compare with the other work areas. Moreover, the mean serum gliadin-specific IgA and IgG and total IgE antibodies were remarkably higher in exposed mill workers compared with the controls (p<0.05).<br /><br /><strong>CONCLUSION: </strong>We clearly demonstrated that workers in Hamadan flour mills are in exposed to a hazardous level of respirable flour dust, receiving the highest level of dust and gliadin in flour packing areas. Furthermore, dust-exposed workers showed upper levels of serum antibodies indicating exposure to higher amounts of allergens than controls. |
| Pmid | 21996928 |
| Wosid | WOS:000297717400002 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Antibodies; Flour; Gliadin; Occupational Exposure; Respiration |
| Is Qa | No |