Activity of T1674 in the in vitro mammalian cell transformation assay in the absence of exogenous metabolic activation
HERO ID
1239572
Reference Type
Technical Report
Subtype
TSCA Submission
Year
1982
Language
English
| HERO ID | 1239572 |
|---|---|
| Material Type | TSCA Submission |
| Year | 1982 |
| Title | Activity of T1674 in the in vitro mammalian cell transformation assay in the absence of exogenous metabolic activation |
| Authoring Organization | Microbiological Associates |
| Publisher Text | Nuodex, Inc |
| City | Piscataway, NJ |
| Abstract | The ability of diisononyl phthalate to induce morphological transformation was evaluated in the Balb/3T3 mouse cell line (Cells Transformation Assay). Based on preliminary toxicity determinations (exposure time = 24hrs), diisononyl phthalate, diluted with acetone, was tested at concentrations of 3 x 10(-2), 0.1, 0.3 or 1ul/ml, resulting in 95% to 76% relative survival. None of the treatments produced significantly greater transformation frequencies (p 0.05) relative to the negative control (acetone). |
| Report Number | EPA/OTS Doc #878210234 |
| Ntis Number | OTS0206260 |
| Tscats Number | TSCATS/018084 |
| Url | https://ntrl.ntis.gov/NTRL/dashboard/searchResults/titleDetail/OTS0206260.xhtml |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Relationship(s) |
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