Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae
Yun, YK; Kim, HK; Kim, JR; Hwang, K; Ahn, YJ
HERO ID
1250077
Reference Type
Journal Article
Year
2012
Language
English
PMID
| HERO ID | 1250077 |
|---|---|
| In Press | No |
| Year | 2012 |
| Title | Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae |
| Authors | Yun, YK; Kim, HK; Kim, JR; Hwang, K; Ahn, YJ |
| Journal | Pest Management Science |
| Volume | 68 |
| Issue | 5 |
| Page Numbers | 788-794 |
| Abstract | <strong>BACKGROUND: </strong>The toxicity to adult Dermatophagoides farinae of allyl isothiocyanate identified in horseradish, Armoracia rusticana, oil and another 27 organic isothiocyanates was evaluated using contact + fumigant and vapour-phase mortality bioassays. Results were compared with those of two conventional acaricides, benzyl benzoate and dibutyl phthalate.<br /><br /><strong>RESULTS: </strong>Horseradish oil (24 h LC(50), 1.54 µg cm(-2)) and allyl isothiocyanate (2.52 µg cm(-2)) were highly toxic. Benzyl isothiocyanate (LC(50) , 0.62 µg cm(-2)) was the most toxic compound, followed by 4-chlorophenyl, 3-bromophenyl, 3,5-bis(trifluoromethyl)phenyl, cyclohexyl, 2-chlorophenyl, 4-bromophenyl and 2-bromophenyl isothiocyanates (0.93-1.41 µg cm(-2)). All were more effective than either benzyl benzoate (LC(50) , 4.58 µg cm(-2)) or dibutyl phthalate (24.49 µg cm(-2)). The structure-activity relationship indicates that types of functional group and chemical structure appear to play a role in determining the isothiocyanate toxicities to adult D. farinae. In the vapour-phase mortality bioassay, these isothiocyanates were consistently more toxic in closed versus open containers, indicating that their mode of delivery was, in part, a result of vapour action.<br /><br /><strong>CONCLUSION: </strong>In the light of global efforts to reduce the level of highly toxic synthetic acaricides in indoor environments, the horseradish oil-derived compounds and the isothiocyanates described herein merit further study as potential acaricides for the control of house dust mite populations as fumigants with contact action. |
| Doi | 10.1002/ps.2327 |
| Pmid | 22102526 |
| Wosid | WOS:000302469500017 |
| Url | https://search.proquest.com/docview/1400122922?accountid=171501 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Source: Web of Science WOS:000302469500017 |
| Is Public | Yes |
| Language Text | English |
| Keyword | Dermatophagoides farinae; botanical acaricide; natural fumigant; Armoracia rusticana; isothiocyanates; structure-activity relationship |
| Is Qa | No |