Ambient air pollution and the risk of stillbirth

Faiz, AS; Rhoads, GG; Demissie, K; Kruse, L; Lin, Y; Rich, DQ

HERO ID

1254455

Reference Type

Journal Article

Year

2012

Language

English

PMID

22811493

HERO ID 1254455
In Press No
Year 2012
Title Ambient air pollution and the risk of stillbirth
Authors Faiz, AS; Rhoads, GG; Demissie, K; Kruse, L; Lin, Y; Rich, DQ
Journal American Journal of Epidemiology
Volume 176
Issue 4
Page Numbers 308-316
Abstract The purpose of the present study was to examine the risk of stillbirth associated with ambient air pollution during pregnancy. Using live birth and fetal death data from New Jersey from 1998 to 2004, the authors assigned daily concentrations of air pollution to each birth or fetal death. Generalized estimating equation models were used to estimate the relative odds of stillbirth associated with interquartile range increases in mean air pollutant concentrations in the first, second, and third trimesters and throughout the entire pregnancy. The relative odds of stillbirth were significantly increased with each 10-ppb increase in mean nitrogen dioxide concentration in the first trimester (odds ratio (OR) = 1.16, 95% confidence interval (CI): 1.03, 1.31), each 3-ppb increase in mean sulfur dioxide concentration in the first (OR = 1.13, 95% CI: 1.01, 1.28) and third (OR = 1.26, 95% CI: 1.03, 1.37) trimesters, and each 0.4-ppm increase in mean carbon monoxide concentration in the second (OR = 1.14, 95% CI: 1.01, 1.28) and third (OR = 1.14, 95% CI: 1.06, 1.24) trimesters. Although ambient air pollution during pregnancy appeared to increase the relative odds of stillbirth, further studies are needed to confirm these findings and examine mechanistic explanations.
Doi 10.1093/aje/kws029
Pmid 22811493
Wosid WOS:000307500500005
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000307500500005
Is Public Yes
Language Text English
Keyword air pollution; fetal death; pregnancy outcomes; stillbirth
Is Qa No