Flow injection potentiometric determination of clobutinol hydrochloride

Issa, YM; Zayed, SI

HERO ID

1323163

Reference Type

Journal Article

Year

2006

Language

English

PMID

18970592

HERO ID 1323163
In Press No
Year 2006
Title Flow injection potentiometric determination of clobutinol hydrochloride
Authors Issa, YM; Zayed, SI
Journal Talanta
Volume 69
Issue 2
Page Numbers 481-487
Abstract New clobutinol (Clob) ion-selective polyvinyl chloride (PVC) membrane electrodes, based on the ion-associates of Clob with phosphotungstic acid or phosphomolybdic acid were prepared using dibutyl phthalate as plasticizing solvent. The electrodes were characterized in terms of membrane composition, temperature and pH. The sensors showed a near-Nernstian response over the concentration ranges (6.31 x 10(-6))-(1.00 x 10(-2)) and (5.01 x 10(-5))-(1.00 x 10(-2))M in the case of clobutinol-phosphotungstate ((Clob)(3)-PT) applying batch and flow injection (FI) analysis, respectively, and (1.58 x 10(-5))-(1.00 x 10(-2)) and (5.01 x 10(-5))-(1.00 x 10(-2))M in case of clobutinol-phosphomolybdate ((Clob)(3)-PM) for batch and FI analysis systems, respectively. The electrodes were successfully applied for the potentiometric determination of ClobCl in pharmaceutical preparation and urine in steady state and flow injection conditions. The electrodes exhibit good selectivity for Clob with respect to a large number of inorganic cations, sugars and amino acids.
Doi 10.1016/j.talanta.2005.10.018
Pmid 18970592
Wosid WOS:000235580300026
Url http://www.sciencedirect.com/science/article/pii/S003991400500696X
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000235580300026
Is Public Yes
Language Text English
Keyword clobutinol hydrochloride; ion-selective electrodes; flow injection analysis; potentiometry