Skin carcinoma in patients with psoriasis treated with topical tar and artificial ultraviolet radiation
Stern, RS; Zierler, S; Parrish, JA
HERO ID
1576543
Reference Type
Journal Article
Year
1980
Language
English
PMID
| HERO ID | 1576543 |
|---|---|
| In Press | No |
| Year | 1980 |
| Title | Skin carcinoma in patients with psoriasis treated with topical tar and artificial ultraviolet radiation |
| Authors | Stern, RS; Zierler, S; Parrish, JA |
| Journal | The Lancet |
| Volume | 1 |
| Issue | 8171 |
| Page Numbers | 732-735 |
| Abstract | A case-control study, consisting of 59 skin cancer patients with severe psoriasis, was conducted to evaluate the effect of treatment with tar and/or artificial ultraviolet radiation on the risk of developing cutaneous carcinoma. Using 924 unmatched controls, we estimated that the crude rate of skin cancer was 2.4-fold for patients with high exposure to tar and ultraviolet radiation, compared with those lacking high exposure. Using a control series of 126 patients matched for age, skin type, region of residence, sex, history of exposure to ionising radiation, and number of 8-methoxypsoralen photochemotherapy treatments, we observed a stronger association (relative rate = 4.7, 95% confidence limits = 2.2 to 10.0). The magnitude of the relative rates argues for continued surveillance for tumours among patients with psoriasis who receive long-term tar or artificial ultraviolet radiation therapy. |
| Pmid | 6103156 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |