Analysis of common and emerging brominated flame retardants in house dust using ultrasonic assisted solvent extraction and on-line sample preparation via column switching with liquid chromatography-mass spectrometry
Kopp, EK; Fromme, H; Voelkel, W
HERO ID
1928011
Reference Type
Journal Article
Year
2012
Language
English
PMID
| HERO ID | 1928011 |
|---|---|
| In Press | No |
| Year | 2012 |
| Title | Analysis of common and emerging brominated flame retardants in house dust using ultrasonic assisted solvent extraction and on-line sample preparation via column switching with liquid chromatography-mass spectrometry |
| Authors | Kopp, EK; Fromme, H; Voelkel, W |
| Journal | Journal of Chromatography A |
| Volume | 1241 |
| Page Numbers | 28-36 |
| Abstract | Brominated flame retardants (BFRs) are persistent and widespread chemicals. Therefore human beings are exposed to BFRs. House dust may be one source of exposure and contains a lot of xenobiotics in relatively high concentrations. In contrast to common GC-MS based methods here an online LC-MS/MS method is presented to quantify 16 BFRs in dust using ultrasonic solvent extraction as a single sample work up step. LOQ from 0.6 (tetrabromobisphenol A) to 80 (polybrominated diphenylethers (BDE 28) ng/g dust were achieved. Data for accuracy, precision and recovery are presented and are comparable to common LC-MS/MS methods in different matrices. In addition 5 real house dust samples were analyzed with high concentration (535 ng/g) for bis(2-ethyl-1-hexyl)tetrabromophthalate which is a novel alternative BFRs to replace common BDE's. |
| Doi | 10.1016/j.chroma.2012.04.022 |
| Pmid | 22546182 |
| Wosid | WOS:000304508800004 |
| Url | /www.sciencedirect.com/science/article/pii/S0021967312005791 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Liquid chromatography; Atmospheric pressure ionization; Mass spectrometry; On-line sample preparation; Brominated flame retardant; House dust |