Durability of aortic valve preservation with root reconstruction for acute type A aortic dissection

Yamanaka, K; Hori, Y; Ikarashi, J; Kusuhara, T; Nakatsuka, D; Hirose, K; Nishina, T; Fujita, M

HERO ID

1976262

Reference Type

Journal Article

Year

2012

Language

English

PMID

22290927

HERO ID 1976262
In Press No
Year 2012
Title Durability of aortic valve preservation with root reconstruction for acute type A aortic dissection
Authors Yamanaka, K; Hori, Y; Ikarashi, J; Kusuhara, T; Nakatsuka, D; Hirose, K; Nishina, T; Fujita, M
Journal European Journal of Cardio-thoracic Surgery
Volume 41
Issue 4
Page Numbers e32-e36
Abstract <strong>OBJECTIVES: </strong>We evaluated the durability of aortic valve preservation with root reconstruction for acute type A aortic dissection (AAAD).<br /><br /><strong>METHODS: </strong>From January 2002 to March 2011, 140 patients [70 males, 68 ± 12 (SD) years] underwent emergency operation for AAAD. The aortic valve was preserved and one or more Valsalva sinuses were reconstructed. Techniques used for reconstruction were valve resuspension and additional reinforcement of the aortic root with Teflon felt patches, and gelatin-resorcinol-formaldehyde-glue (GRF-glue) was used for mending the dissection. The mean follow-up period was 44.0 ± 26.2 months. We classified the degree of aortic regurgitation (AR) into four grades (0, 1+, 2+ and 3+) using echocardiography. Based on a retrospective analysis of pre-operative echocardiographic findings, the 127 survivors were divided into two groups: group 1 (G1) included 98 patients with 0 or 1+ AR, and group 2 (G2) 29 patients with 2+ or 3+ AR. In addition, we measured the post-operative native aortic root dimension of AAAD patients with use of echocardiography or CT scan.<br /><br /><strong>RESULTS: </strong>The operative mortality rate was 9.3% (13/140). Freedom from aortic root re-operation was 100%. Aortic root pseudoaneurysm formation and severe AR requiring aortic valve replacement did not occur. Pre-operative AR of 0.2 ± 0.4 in G1 did not deteriorate (0.5 ± 0.5 at discharge, 0.4 ± 0.4 at follow-up). Meanwhile, pre-operative AR of 2.4 ± 0.5 in G2 improved to 0.6 ± 0.5 (P &lt; 0.05) at discharge and 1.0 ± 0.6 (P &lt; 0.05) at follow-up. The native aortic root dimension in G2 at follow-up was significantly larger than G1 (36.0 ± 4.7 vs. 33.9 ± 5.0 mm).<br /><br /><strong>CONCLUSIONS: </strong>Aortic valve preservation and root reconstruction appear to be an appropriate surgical approach to AAAD.
Doi 10.1093/ejcts/ezr292
Pmid 22290927
Wosid WOS:000302021300002
Is Certified Translation No
Dupe Override No
Comments Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery ISSN: 1873-734X
Is Public Yes
Language Text English
Keyword Acute Disease; Aged, 80 and over; Aneurysm, Dissecting/complications/pathology/ surgery; Aorta/pathology/surgery; Aortic Aneurysm/complications/pathology/ surgery; Aortic Valve/ surgery; Aortic Valve Insufficiency/etiology/ultrasonography; Blood Vessel Prosthesis Implantation/adverse effects/ methods; Echocardiography, Transesophageal; Emergencies; Epidemiologic Methods; Middle Aged; Sinus of Valsalva/surgery; Treatment Outcome