Contribution of radon and radon daughters to respiratory cancer
Harley, N; Samet, JM; Cross, FT; Hess, T; Muller, J; Thomas, D
| HERO ID | 23142 |
|---|---|
| In Press | No |
| Year | 1986 |
| Title | Contribution of radon and radon daughters to respiratory cancer |
| Authors | Harley, N; Samet, JM; Cross, FT; Hess, T; Muller, J; Thomas, D |
| Journal | Environmental Health Perspectives |
| Volume | 70 |
| Page Numbers | 17-21 |
| Abstract | The influence of radon and radon daughters on development of respiratory cancer is reviewed. Epidemiological studies thus far indicate that excess lung cancer mortality is connected with miners having cumulative radon (10043922) daughter exposures somewhat below 100 working level month (WLM). A WLM is defined as a 170 hour working month exposure to alpha radiation from radon daughters equal to 1.3 x 10(5) megaelectron volts emitted in 1 liter of air. Special groups which seem to be at particular risk from radon daughters include smokers or individuals with pulmonary disease. Their increased risk results from stimulation of cell division in the bronchial tree. An additive rather than a multiplicative model has been gaining support to illustrate the connection between smoking and radon daughter induced lung cancer. It is recommended that a national radon survey be conducted seeking information on the radon concentration in air and water in homes in the United States. Such a survey will locate areas of high geologic radon exposure that would not be detected by special purpose surveys. International pooling of data is suggested to improve epidemiologic information already gathered. Epidemiologic studies of miners which are currently in progress should be continued and additional populations should be placed under study if the exposure pattern justifies such study. The conducting of experimental animal studies is also recommended so that modifications can be made in human exposures and thereby lessen the likelihood of lung cancer developing in exposed populations. The development of a personal dosimeter for occupational radon exposure is encouraged. |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Environ. Health Perspect. 70: 17-21. |
| Is Public | Yes |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>DCN-154937</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Pulmonary system disorders</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Neoplastic agents</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Risk factors</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Mine workers</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Lung cancer</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Radionuclides</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Uranium mining</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Uranium miners</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Carcinogenesis</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Radon daughters</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Radiation hazards</kw> |
| Is Qa | No |