APPLICATIONS OF IMMUNOHISTOCHEMISTRY IN RODENT TUMOR PATHOLOGY

Ward, JM; Rehm, S

HERO ID

2347169

Reference Type

Journal Article

Year

1990

PMID

2098275

HERO ID 2347169
In Press No
Year 1990
Title APPLICATIONS OF IMMUNOHISTOCHEMISTRY IN RODENT TUMOR PATHOLOGY
Authors Ward, JM; Rehm, S
Journal Experimental Pathology
Volume 40
Issue 4
Page Numbers 301-312
Abstract Immunohistochemistry can serve as a valuable adjunct to rodent tumor pathology. Specific antigens may be localized to cells and tissues in normal organs, preneoplastic lesions, and benign and malignant tumors. The immunoreactivity of polyclonal and monoclonal antibodies to these antigens provide a more accurate basis for tumor diagnosis and aid in understanding pathogenesis. Ultimately, the application of more precise understanding of tumor histogenesis and diagnosis will lead to more accurate interpretations of tumor incidence data for safety assessment in toxicology.
Pmid 2098275
Wosid WOS:A1990EU35200015
Is Certified Translation No
Dupe Override No
Is Public Yes
Keyword FCC = FOLLICULAR CENTER CELL; LGL = LARGE ANTIGRANULOCYTES LYMPHOCYTE; GSTP = GLUTATHIONE S-TRANSFERASE, PLACENTAL FORM; AFP = ALPHA-FETOPROTEIN; GFAP = GLIAL FIBRILLARY ACIDIC PROTEIN