Concentration-time mortality response relationship of irritant and systemically acting vapours and gases
ten Berge, WF; Zwart, A; Appelman, LM
| HERO ID | 25664 |
|---|---|
| In Press | No |
| Year | 1986 |
| Title | Concentration-time mortality response relationship of irritant and systemically acting vapours and gases |
| Authors | ten Berge, WF; Zwart, A; Appelman, LM |
| Journal | Journal of Hazardous Materials |
| Volume | 13 |
| Issue | 3 |
| Page Numbers | 301-309 |
| Abstract | This report presents the re-evaluation of the raw data of previously published acute inhalation toxicity studies of some volatile industrial chemicals. In these studies both concentration and exposure time were varied. The raw data were obtained from an extensive literature search and were subjected to probit analysis. The results show that the product of concentration and exposure time (ct) is not always a good parameter for predicting the mortality response (Haber's rule). On the contrary, the term cnt, in which the exponent n is different from 1, often predicts the response very well. |
| Doi | 10.1016/0304-3894(86)85003-8 |
| Wosid | WOS:A1986D846100003 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | ECRIB.J. Hazard. Mater. 13: 301-309. |
| Is Public | Yes |
| Language Text | English |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>Biochemistry-Gases (1970- )</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Biochemical Studies-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Pathology</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Pathology</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Respiratory System-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Routes of Immunization</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Toxicology-General</kw> |
| Is Peer Review | Yes |
| Relationship(s) |
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