Inhalation studies with benzo[a]pyrene in Syrian golden hamsters

Thyssen, J; Althoff, J; Kimmerle, G; Mohr, U

HERO ID

27296

Reference Type

Journal Article

Year

1981

Language

English

PMID

6937711

HERO ID 27296
In Press No
Year 1981
Title Inhalation studies with benzo[a]pyrene in Syrian golden hamsters
Authors Thyssen, J; Althoff, J; Kimmerle, G; Mohr, U
Journal Journal of the National Cancer Institute
Volume 66
Issue 3
Page Numbers 575-577
Abstract Groups of Syrian golden hamsters were exposed by inhalation to benzo[a]pyrene (BP) in concentrations of 2.2, 9.5, and 45.6 mg/m3 air. Although 45.6 mg BP/m3 air was carcinogenic and toxic, 2.2 mg BP/m3 air led to no neoplastic response. The highest tumor incidence was seen in the group exposed to 9.5 mg BP/m3 air. Average survival times were similar in the controls (not exposed to BP) and in the 2 groups given 2.2 and 9.5 mg BP/m3 air. Exposure-related neoplasms were found in the nasal cavity, larynx, pharynx, esophagus, and forestomach. Bronchogenic tumors did not develop.
Doi 10.1093/jnci/66.3.575
Pmid 6937711
Wosid WOS:A1981LF95800024
Url https://www.proquest.com/docview/75576845?accountid=171501&bdid=13857&_bd=SGAT5DliAMw%2BfXe8nDVFugL2RD0%3D
Is Certified Translation No
Dupe Override No
Comments a in [a] is italicized.JNCI J. Natl. Cancer Inst. 66: 575-577.Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0019480625&doi=10.1093%2fjnci%2f66.3.575&partnerID=40&md5=868c523ec22bda74fc42cfeb334f45cc
Is Public Yes
Language Text English
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