[Guinea-pig repeated open patch test]
Okamoto, K; Nakamura, K; Yoshikawa, H; Tsuyoshi, T; Nakano, E; Ueda, S
HERO ID
3041274
Reference Type
Journal Article
Year
1984
Language
Japanese
| HERO ID | 3041274 |
|---|---|
| In Press | No |
| Year | 1984 |
| Title | [Guinea-pig repeated open patch test] |
| Authors | Okamoto, K; Nakamura, K; Yoshikawa, H; Tsuyoshi, T; Nakano, E; Ueda, S |
| Journal | Skin Research |
| Volume | 26 |
| Issue | 5 |
| Page Numbers | 1109-1118 |
| Abstract | We conducted the guinea pig three days repeated open patch test using the samples of three polyols (propylene glycol, 1, 3-butylene glycol and glycerin) as is and 10% in distilled water and of three hydrocarbons (liquid paraffin #72, squalane and pristane). Tests were performed in three labolatories. Comparing the mean reaction of each three laboratories based on Japanese standard, the all samples of the polyols were weak in the skin reactions and no clear differences of reactions were seen. On the other hand, hydrocarbons showed irritant reactions and the order of irritancy was pristane, liquid paraffin #72 and squalane. By the Draize standard, polyols showed slight erythema and no edema, and hydrocarbons showed parallel score between erythema and edema, and the irritation order of three hydrocarbons was the same as that of the Japanese standard. Though some differences were shown in the grade of reactions between three laboratories, there was shown the same order as to the irritation grade of three chemicals. |
| Doi | 10.11340/skinresearch1959.26.1109 |
| Url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85007968289&doi=10.11340%2fskinresearch1959.26.1109&partnerID=40&md5=0702409d3adde372f92a62175c09f3a0 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | Japanese |