The application of directly suspended droplet microextraction for the evaluation of phthalic acid esters in cow's milk by gas chromatography mass spectrometry
Liu, D; Min, S; Ping, H; Song, X
HERO ID
3350303
Reference Type
Journal Article
Year
2016
Language
English
PMID
| HERO ID | 3350303 |
|---|---|
| In Press | No |
| Year | 2016 |
| Title | The application of directly suspended droplet microextraction for the evaluation of phthalic acid esters in cow's milk by gas chromatography mass spectrometry |
| Authors | Liu, D; Min, S; Ping, H; Song, X |
| Journal | Journal of Chromatography A |
| Volume | 1443 |
| Page Numbers | 66-74 |
| Abstract | A simple and rapid method was developed for evaluating 16 phthalic acid esters (PAEs) at the μg/kg level in a complex milk matrix using directly suspended droplet microextraction-gas chromatography mass spectrometry (DSDME-GC-MS). The different parameters for extraction and for the DSDME experiment were optimized, including You are free to submit the revised manuscript at a later date as a new submission. 10g/L trichloroacetic acid concentration, 100μL cyclohexane micro-droplet organic solvent, 1100rpm stirring speed, 10min extraction time and no salt amount. Validation experiments showed good linearity (γ>0.9878, 0.002-0.4μg/mL), satisfactory precision (RSD<11%), and good accuracy (relative recovery of 70.2-108%) when analyzing milk samples using the optimized method. The limits of detection (LODs) ranged between 0.001 and 0.2μg/L, and the limits of quantification (LOQs) ranged between 0.003 and 0.7μg/L for 15 PAEs. Dinonyl phthalate (DINP) had a low response and did not have good linearity. The proposed method was successfully applied for the analysis of PAEs in real milk samples. |
| Doi | 10.1016/j.chroma.2016.03.062 |
| Pmid | 27025790 |
| Wosid | WOS:000374362600009 |
| Url | http://www.sciencedirect.com/science/article/pii/S0021967316303442 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Phthalic acid esters PAEs; Directly suspended droplet microextraction; DSDME; Milk |
| Relationship(s) |
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