An agile, simplified and sonication mediated one-pot aqueous extraction and antibacterial assessment of predominant Korean mushrooms
Shang, X; Muthu, M; Keum, Y; Chun, S; Gopal, J
| HERO ID | 3350598 |
|---|---|
| In Press | No |
| Year | 2016 |
| Title | An agile, simplified and sonication mediated one-pot aqueous extraction and antibacterial assessment of predominant Korean mushrooms |
| Authors | Shang, X; Muthu, M; Keum, Y; Chun, S; Gopal, J |
| Journal | RSC Advances |
| Volume | 6 |
| Issue | 15 |
| Page Numbers | 12143-12157 |
| Abstract | Solvent-based extractions have always held the upper hand when it comes to mushrooms. Assimilating the fact that mushrooms are a part of culinary components cooked in water and not in solvents; solvent-based extraction becomes a priority. Effective water based extraction stretches 24 h, leaving space for prospective improvising through analytical interference. We have demonstrated the effective downsizing of the extraction time from 24 h to 2 min via sonication based extraction strategies. A water bath-based method could achieve effective extraction at 30 min, whereas further enhancement was seen through the use of a probe sonication approach to 2 min. The extraction efficiency was tested based on the antibacterial activity of mushroom extracts against two pathogens, Streptococcus mutans and Pseudomonas aeruginosa. The systematic optimization of the sonication approach and a comparison of their effectiveness versus conventional approaches are demonstrated. The bioactive components in the extracts obtained via the different extractions have been characterized using biochemical characterization as well as GC-MS analysis. The enhanced extraction and potent role of butanoic acid, hexadecanoic acid, octadecanoic acid and 1,2-benzenedicarboxylic acid were confirmed to be behind the success behind the sonication mediated extraction. |
| Doi | 10.1039/c5ra25514g |
| Wosid | WOS:000369545800030 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |