Optimized method avoiding solvent-induced response enhancement in the analysis of volatile and semi-volatile polyfluorinated alkylated compounds using gas chromatography-mass spectrometry
Dreyer, A; Temme, C; Sturm, R; Ebinghaus, R
| HERO ID | 3514999 |
|---|---|
| In Press | No |
| Year | 2008 |
| Title | Optimized method avoiding solvent-induced response enhancement in the analysis of volatile and semi-volatile polyfluorinated alkylated compounds using gas chromatography-mass spectrometry |
| Authors | Dreyer, A; Temme, C; Sturm, R; Ebinghaus, R |
| Journal | Journal of Chromatography A |
| Volume | 1178 |
| Issue | 1-2 |
| Page Numbers | 199-205 |
| Abstract | A method for the analysis of airborne (semi-)volatile polyfluorinated alkyl substances (PFASs) was optimized to avoid solvent-induced response enhancements as observed using ethyl acetate as extraction solvent (recoveries up to 300%, likely due to acetic acid as impurity). Of nine solvents tested, only the use of acetone, dichloromethane, methyl tert-butyl ether, and acetone:petroleum ether (1:1, v/v) resulted in recoveries below 100% and acetone:methyl tert-butyl ether (1:1, v/v) was chosen as suited extraction solvent. An appropriate GC capillary column and the application of mass-labelled internal standards appeared to be essential for these analyses. Instrumental limits of detection of <0.2 pg (dimethylperfluoroocatanesulfonamide, ethyl-[(2)H(5)]perfluorooctanesulfonamide, methyl-[(2)H(3)]perfluorooctanesulfonamide) to 8.2 pg (perfluorooctanesulfonamide) and LOQ of 0.4 pg (dimethylperfluoroocatanesulfonamide, ethyl-[(2)H(5)]perfluorooctanesulfonamide, methyl-[(2)H(3)]perfluorooctanesulfonamide) to 16.4 pg (perfluorooctanesulfonamide) were determined. |
| Doi | 10.1016/j.chroma.2007.11.050 |
| Pmid | 18082170 |
| Wosid | WOS:000252477400024 |
| Url | http://www.sciencedirect.com/science/article/pii/S0021967307020006 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Fluorotelomer alcohols; Perfluoroalkyl sulfonamides; Perfluoroalkyl sulfonamido ethanols; Matrix effect; Acetic acid |