A two-photon fluorescent probe for imaging hydrogen sulfide in living cells
Liu, T; Zhang, X; Qiao, Q; Zou, C; Feng, Lei; Cui, J; Xu, Z
| HERO ID | 3575754 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | A two-photon fluorescent probe for imaging hydrogen sulfide in living cells |
| Authors | Liu, T; Zhang, X; Qiao, Q; Zou, C; Feng, Lei; Cui, J; Xu, Z |
| Journal | Dyes and Pigments |
| Volume | 99 |
| Issue | 3 |
| Page Numbers | 537-542 |
| Abstract | Fluorescent probes for hydrogen sulfide have received considerable attention because of the biological significance of H2S recognized recently. Two-photo microscopy offers advantages of increased penetration depth, localized excitation, and prolonged observation time. However, two-photon fluorescent probes for H2S are still rare. In this work, we introduced a dinitrophenyl ether group into the 4-position of 1,8-naphthalimide, which acts as the H2S reactive site, to efficiently yield compound NI-NHS as a two-photo fluorescent probe for H2S. The probe NI-NHS has a high selectivity for H2S over competitive anions and sulfide-containing analytes. This probe exhibits turn-on fluorescence detection of H2S in bovine serum and two-photon fluorescent imaging of H2S in living cells. (C) 2013 Elsevier Ltd. All rights reserved. |
| Doi | 10.1016/j.dyepig.2013.06.031 |
| Wosid | WOS:000327560200003 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Keyword | Two-photon fluorescence microscopy; Fluorescent probes; Hydrogen sulfide; Thiolysis; High selectivity; Cells imaging |