Highly efficient regio and diastereoselective synthesis of functionalized bis-spirooxindoles and their antibacterial properties
Ramesh, P; Rao, KS; Trivedi, R; Kumar, BS; Prakasham, RS; Sridhar, B
| HERO ID | 3758767 |
|---|---|
| In Press | No |
| Year | 2016 |
| Title | Highly efficient regio and diastereoselective synthesis of functionalized bis-spirooxindoles and their antibacterial properties |
| Authors | Ramesh, P; Rao, KS; Trivedi, R; Kumar, BS; Prakasham, RS; Sridhar, B |
| Journal | RSC Advances |
| Volume | 6 |
| Issue | 32 |
| Page Numbers | 26546-26552 |
| Abstract | A simple, efficient, regioselective and diastereoselective method has been developed for the synthesis of diversely functionalized spirooxindole-pyrrolidines using 0.5 mol% of ceric ammonium nitrate in aqueous medium. All the new compounds are tested for in vitro antimicrobial activity. All the synthesized products have shown good antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Micrococcus luteus (Gram-positive organisms), Salmonella paratyphi, Pseudomonas aeruginosa and Salmonella typhi (Gram-negative organism). |
| Doi | 10.1039/c6ra00613b |
| Wosid | WOS:000372253700009 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |