Trace-level determination of 1,4-dioxane in water by isotopic dilution GC and GC-MS
Draper, WM; Dhoot, JS; Remoy, JW; Perera, SK
HERO ID
3798940
Reference Type
Journal Article
Year
2000
Language
English
PMID
| HERO ID | 3798940 |
|---|---|
| In Press | No |
| Year | 2000 |
| Title | Trace-level determination of 1,4-dioxane in water by isotopic dilution GC and GC-MS |
| Authors | Draper, WM; Dhoot, JS; Remoy, JW; Perera, SK |
| Journal | Analyst |
| Volume | 125 |
| Issue | 8 |
| Page Numbers | 1403-1408 |
| Abstract | The volatile and polar solvent 1,4-dioxane has recently been reported as a contaminant of ground and surface waters, establishing the need to determine this substance in drinking water. This investigation established that 1,4-dioxane can be determined in water by various techniques including direct aqueous injection (DAI) gas chromatography (GC) and purge and trap GC-mass spectrometry (MS). Purge and trap GC-MS is limited by 1,4-dioxane's poor purge efficiency, resulting in detection limits up to 100 times greater than the efficiently purged volatile organic compounds. To attain the sensitivity required for drinking water monitoring, a method based on continuous liquid-liquid extraction with dichloromethane was developed. Isotope dilution was more accurate and reproducible than quantification with external standards, and the improvement in precision led to a lower method detection limit, 0.2 mu g L-1, using a quadrupole ion trap instrument in the electron ionization mode. Isotope dilution accuracy approached 100% in ppb determinations. Isotopic dilution quantification was also possible using a non-selective GC detector owing to the high efficiency of capillary GC columns that resolve the deuterium-labeled solvent from the natural isotopes. |
| Doi | 10.1039/b002345k |
| Pmid | 11002923 |
| Wosid | WOS:000088527900008 |
| Url | http://xlink.rsc.org/?DOI=b002345k |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: Analyst (Cambridge UK) ISSN: |
| Is Public | Yes |
| Language Text | English |
| Keyword | Chemical analysis (see also Individual techniques) Volatile materials Gas chromatography Solvents Spectrometry (Mass) Water analysis |