Cu(OTf)2-catalyzed selective arene C-H bond hydroxylation and nitration with KNO2 as an ambident O- and N-nucleophile via a Cu(II)-Cu(III)-Cu(I) mechanism
Zhang, H; Zhao, L; Wang, DX; Wang, MX
| HERO ID | 3806261 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | Cu(OTf)2-catalyzed selective arene C-H bond hydroxylation and nitration with KNO2 as an ambident O- and N-nucleophile via a Cu(II)-Cu(III)-Cu(I) mechanism |
| Authors | Zhang, H; Zhao, L; Wang, DX; Wang, MX |
| Journal | Organic Letters |
| Volume | 15 |
| Issue | 15 |
| Page Numbers | 3836-3839 |
| Abstract | Cu(OTf)2-catalyzed selective arene C-H bond hydroxylation and nitration reactions of azacalix[1]arene[3]pyridines were achieved using KNO2 as an ambident O- and N-nucleophile under very mild aerobic conditions to yield functionalized azacalixaromatics. The reaction, which selectivity between hydroxylation and nitration was modulated by the reaction medium employed, proceeded through a Cu(II)-Cu(III)-Cu(I) mechanism. |
| Doi | 10.1021/ol401453f |
| Pmid | 23848544 |
| Wosid | WOS:000322853000009 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |