Reproducibility discrepancies following reanalysis of raw data for a previously published study on diisononyl phthalate (DINP) in rats
Chen, M; Alyea, R; Morfeld, P; Otter, R; Kemmerling, J; Palermo, C
HERO ID
3859100
Reference Type
Journal Article
Year
2017
Language
English
PMID
| HERO ID | 3859100 |
|---|---|
| In Press | No |
| Year | 2017 |
| Title | Reproducibility discrepancies following reanalysis of raw data for a previously published study on diisononyl phthalate (DINP) in rats |
| Authors | Chen, M; Alyea, R; Morfeld, P; Otter, R; Kemmerling, J; Palermo, C |
| Journal | Data in Brief |
| Volume | 13 |
| Page Numbers | 208-213 |
| Abstract | A 2011 publication by Boberg et al. entitled "Reproductive and behavioral effects of diisononyl phthalate (DINP) in perinatally exposed rats" [1] reported statistically significant changes in sperm parameters, testicular histopathology, anogenital distance and retained nipples in developing males. Using the statistical methods as reported by Boberg et al. (2011) [1], we reanalyzed the publically available raw data ([dataset] US EPA (United States Environmental Protection Agency), 2016) [2]. The output of our reanalysis and the discordances with the data as published in Boberg et al. (2011) [1] are highlighted herein. Further discussion of the basis for the replication discordances and the insufficiency of the Boberg et al. (2011) [1] response to address them can be found in a companion letter of correspondence (doi: 10.1016/j.reprotox.2017.03.013.; (Morfeld et al., 2011) [3]). |
| Doi | 10.1016/j.dib.2017.05.043 |
| Pmid | 28616453 |
| Wosid | BCI:BCI201900149147 |
| Url | https://linkinghub.elsevier.com/retrieve/pii/S2352340917302342 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Reproducibility; Reproductive toxicology; Statistical reanalysis; Diisononyl phthalate (DINP) |
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