Chemical, physical, and toxicological characterization of fumes produced by heating tetrafluoroethene homopolymer and its copolymers with hexafluoropropene and perfluoro(propyl vinyl ether)
Seidel, WC; Scherer, KV, Jr; Cline, D, Jr; Olson, AH; Bonesteel, JK; Church, DF; Nuggehalli, S; Pryor, WA
HERO ID
44898
Reference Type
Journal Article
Year
1991
Language
English
PMID
| HERO ID | 44898 |
|---|---|
| In Press | No |
| Year | 1991 |
| Title | Chemical, physical, and toxicological characterization of fumes produced by heating tetrafluoroethene homopolymer and its copolymers with hexafluoropropene and perfluoro(propyl vinyl ether) |
| Authors | Seidel, WC; Scherer, KV, Jr; Cline, D, Jr; Olson, AH; Bonesteel, JK; Church, DF; Nuggehalli, S; Pryor, WA |
| Journal | Chemical Research in Toxicology |
| Volume | 4 |
| Issue | 2 |
| Page Numbers | 229-236 |
| Abstract | #Submicrometer solid-particle (fume) aerosols with up to about 10(8) particles/cm3 are formed when dilute vapors of low molecular weight (MW) (ca. 5000-10 000) perfluoro polymers condense in air. The aerosol (e.g., 0.2 mg/m3) formed from these vapors is highly toxic to laboratory rats by inhalation (30-min exposure) when fresh but loses toxic in minutes, apparently owing to coagulation. These fumes may result from (a) pyrolysis of tetrafluoroethene homopolymer or tetrafluoroethene-hexafluoropropene copolymer or (b) evaporation, at 200-230-degrees-C, of isolated low MW polymer or low MW polymer present in perfluoro polymer resins. Some perfluoro polymer fume aerosols contain reactive functional group, but others without detectable reactive groups are at least as toxic. |
| Doi | 10.1021/tx00020a017 |
| Pmid | 1664259 |
| Wosid | WOS:A1991FC03000017 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | ECRIB.Chem. Res. Toxicol. 4: 229-236. |
| Is Public | Yes |
| Language Text | English |
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