Adrenocortical response to stress in rats exposed to lead nitrate
Agrawal, R; Chansouria, JPN
HERO ID
48413
Reference Type
Journal Article
Year
1989
Language
English
PMID
| HERO ID | 48413 |
|---|---|
| In Press | No |
| Year | 1989 |
| Title | Adrenocortical response to stress in rats exposed to lead nitrate |
| Authors | Agrawal, R; Chansouria, JPN |
| Journal | Research Communications in Molecular Pathology and Pharmacology |
| Volume | 65 |
| Issue | 2 |
| Page Numbers | 257-260 |
| Abstract | In lead nitrate treated animals the basal adrenal corticosterone levels were significantly increased alongwith the lowering of adrenal ascorbic acid. The basal plasma corticosterone levels did not change significantly in these rats. Following exposure to immobilization stress, the adrenal corticosterone levels were more markedly enhanced in lead nitrate treated rats than normal stressed animals. On the other hand, plasma corticosterone response to stress was found to be less pronounced in treated rats in comparison to normal stressed rats. The adrenal ascorbic acid contents significantly decreased in both control and treated rats following exposure to stress. These observations suggest that adrenocortical response to stress is considerably altered in lead nitrate treated animals. |
| Pmid | 2587844 |
| Wosid | BCI:BCI198937091680 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024376406&partnerID=40&md5=5999d8a1216eb7cfde7c056a0c98281d |
| Is Public | Yes |
| Language Text | English |
| Keyword | ascorbic acid; corticosterone; lead nitrate; adrenal cortex; animal experiment; male; nonhuman; priority journal; rat; stress; Adrenal Cortex; Animal; Ascorbic Acid; Corticosterone; Lead; Male; Nitrates; Organ Weight; Rats; Restraint, Physical; Stress, Psychological |
| Is Peer Review | Yes |