Antimicrobial activity of Araucaria cunninghamii Sweet and the chemical constituents of its twigs and leaves
Chen, J; Yang, ML; Zeng, J; Gao, K
HERO ID
4851281
Reference Type
Journal Article
Year
2013
Language
English
| HERO ID | 4851281 |
|---|---|
| In Press | No |
| Year | 2013 |
| Title | Antimicrobial activity of Araucaria cunninghamii Sweet and the chemical constituents of its twigs and leaves |
| Authors | Chen, J; Yang, ML; Zeng, J; Gao, K |
| Journal | Phytochemistry Letters |
| Volume | 6 |
| Issue | 1 |
| Page Numbers | 41-45 |
| Abstract | The present study was aimed at the identification of antimicrobial components from Araucaria cunninghamii with an activity-guided purification process. Eight compounds were obtained from the most active n-BuOH fraction and identified as the new compound 4-n-butoxyl-phenylpropanetriol (1), together with seven known compounds (2a8). These compounds were tested for antimicrobial activities against five bacteria and four plant pathogenic fungi. Within the series of compounds tested, compound 2 was the most active, particularly displaying moderate antibacterial activities against Erwinia carotovora and Bacillus subtilis with MICs 7.8 and 15.5 mu g/ml. Moreover, this compound exhibited inhibitory activities against four plant pathogenic fungi: Helminthosporium sativum, Rhizoctonia solani, Fusarium oxysporum f. sp. Niveum and Fusarium oxysporum f. sp. Cubense, with EC50 values of 42.3, 90.0, 62.7 and 100.2 mu g/ml. To our knowledge, this is the first report that the n-BuOH fraction and compound 2 from A. cunninghamii showed inhibitory activity against plant pathogenic fungi. |
| Doi | 10.1016/j.phytol.2012.10.013 |
| Wosid | WOS:000314477900010 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |