Study of ligand and base effects on enantioselective allylation catalyzed by Pd(0) phosphine complexes in [bmim][PF6] ionic liquid

Kmentova, I; Gotov, B; Solcaniova, Eva; Toma, S

HERO ID

4932993

Reference Type

Journal Article

Year

2002

HERO ID 4932993
In Press No
Year 2002
Title Study of ligand and base effects on enantioselective allylation catalyzed by Pd(0) phosphine complexes in [bmim][PF6] ionic liquid
Authors Kmentova, I; Gotov, B; Solcaniova, Eva; Toma, S
Journal Green Chemistry
Volume 4
Issue 2 (2002)
Page Numbers 103-106
Abstract Enantioselective Pd-catalyzed allylic substitution of ()-()-1,3-diphenyl-3-acetoxyprop-1-ene with dimethyl malonate was studied in 3-butyl-1-methylimidazolium hexafluorophosphate ([bmim][PF]) as an ionic liquid. The reactions were catalyzed by Pd() complexes of three homochiral ferrocenylphosphine ligands, (,)-iPr-Phosferrox, (,)-iPr-Phosferrox, (,)-BCyPFA and ()-BINAP. Potassium carbonate and bis(trimethylsilyl)acetamide (BSA)/AcOK were tested as the bases and simple optimization of the reaction procedure was performed. Experiments with other soft nucleophiles also were carried out under optimized conditions.
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Keyword green development; Potassium