New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on beta-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone

Di Matteo, L; Christodoulakis, O; Filosa, R; De Caprariis, P; Di Mola, A; Vasca, E; Massa, A

HERO ID

4936050

Reference Type

Journal Article

Year

2014

HERO ID 4936050
In Press No
Year 2014
Title New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on beta-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone
Authors Di Matteo, L; Christodoulakis, O; Filosa, R; De Caprariis, P; Di Mola, A; Vasca, E; Massa, A
Journal Journal of Coordination Chemistry
Volume 67
Issue 13
Page Numbers 2217-2228
Abstract The complexing capability of beta-diketone-3-substituted phthalides (isobenzofuranone) or isoindolinones toward Cu(II), Fe(III), Al(III), and Zn(II) salts has been highlighted by UV-vis spectroscopic studies. Conversely, heterocyclic analogs substituted with dimethyl malonate showed no complexing ability. Further insights have been given by the determination of equilibrium constants and distribution diagram, while the synthesis, isolation, and characterization of Cu(II)-beta-diketonate-isoindolinone complex has been achieved via a convenient modification of standard procedures. Moreover, in silico evaluation of bioavailability of the ligands is also discussed for potential pharmacological applications.
Doi 10.1080/00958972.2014.939075
Wosid WOS:000341444100004
Is Certified Translation No
Dupe Override No
Is Public Yes
Keyword beta-diketonate; Metal complexes; Heterocycles