2,6,10,15,19,23-hexamethyltetracosane: genetic toxicity: in vitro: 002 key | experimental result

HERO ID

5016723

Reference Type

Technical Report

Year

2011

Language

English

HERO ID 5016723
Year 2011
Title 2,6,10,15,19,23-hexamethyltetracosane: genetic toxicity: in vitro: 002 key | experimental result
Authoring Organization European Chemicals Agency
Abstract Assessment of mutagenic activity of squalane was conduced on "Salmonella typhimurium his-" and "Escherichia coli WP2(uvrA)" strains according to the OECD guideline n°471. There is no signicant difference between the number of spontaneaous reversions, the number of reversions obtained in the positive controls (with or without metabolica cativation), and the mean of corresponding experimental historic values obtained in the laboratory. There is no evidence of any increase of number of revertant colonies in the presence of the test substance (5000, 1000, 500, 100 and 50 µg) with or without metabolic activation for bacterial strains in Salmonella typhimurium TA1535, TA97a, TA98, TA100 and Escherichia coli WP2(uvrA).
Url https://echa.europa.eu/registration-dossier/-/registered-dossier/14412/7/7/2/?documentUUID=e4b910bb-72b8-4f60-8cff-8b4e61e6fed7
Is Certified Translation No
Dupe Override No
Number Of Pages 4
Is Public Yes
Language Text English