Coordination-driven self-assembly of ruthenium(ii) architectures: synthesis, characterization and cytotoxicity studies

Adeyemo, AA; Shettar, A; Bhat, IA; Kondaiah, P; Mukherjee, PS

HERO ID

5238482

Reference Type

Journal Article

Year

2018

Language

English

PMID

29901668

HERO ID 5238482
In Press No
Year 2018
Title Coordination-driven self-assembly of ruthenium(ii) architectures: synthesis, characterization and cytotoxicity studies
Authors Adeyemo, AA; Shettar, A; Bhat, IA; Kondaiah, P; Mukherjee, PS
Journal Dalton Transactions (Online)
Volume 47
Issue 25
Page Numbers 8466-8475
Abstract Coordination-driven self-assembly of organometallic η6-arene ruthenium(ii) supramolecular architectures (MA1-MA4) was carried out by employing dinuclear ruthenium acceptors [Ru2(μ-η4-C2O4)(CH3OH)2(η6-p-cymene)2](CF3SO3)2 (Rua), [Ru2(μ-η4-C6H2O4)(CH3OH)2(η6-p-cymene)2](CF3SO3)2 (Rub), [Ru2(dhnq)(H2O)2(η6-p-cymene)2](CF3SO3)2 (Ruc) and [Ru2(dhtq)(H2O)2(η6-p-cymene)2](CF3SO3)2 (Rud) separately with a new tetratopic donor (TD) in methanol at room temperature [TD = N,N,N',N'-tetra(pyridin-4-yl)-[1,1'-biphenyl]-4,4'-diamine]. All the coordination architectures were characterized by using spectroscopic techniques. The potency of these self-assembled architectures against human cervical cancer HeLa and human lung adenocarcinoma A549 cell lines is explored in vitro using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), annexin V-FITC/PI and 2',7'-dichlorofluorescein-diacetate assays.
Doi 10.1039/c8dt00962g
Pmid 29901668
Wosid WOS:000436302700034
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English