Retrograde enhancement of memory by mild flurothyl treatment in the chick
Cherkin, A; Meinecke, RO; Garman, MW
| HERO ID | 5383261 |
|---|---|
| In Press | No |
| Year | 1975 |
| Title | Retrograde enhancement of memory by mild flurothyl treatment in the chick |
| Authors | Cherkin, A; Meinecke, RO; Garman, MW |
| Journal | Physiology & Behavior |
| Volume | 14 |
| Issue | 2 |
| Page Numbers | 151-158 |
| Abstract | Strong flurothyl treatment (1.7% v/v for 8 min) produces retrograde amnesia in chicks when administered as long as 24 hr after one-trial avoidance training with a strongly aversive stimulus. Mild flurothyl treatment (0.2% v/v for 8 min) produced retrograde enhancement when administered as long as 16 min after similar training with a moderately aversive stimulus. The moderate training followed by mild flurothyl treatment enhanced 24-hr retention to the level found after strong training alone. Enhanced retention persisted for at least 72 hr; nonspecific performance effects faded within 48 hr. The predominant dose-dependent and time-dependent enhancement effect of mild flurothyl treatment is interpreted as improved memory consolidation. |
| Doi | 10.1016/0031-9384(75)90159-6 |
| Pmid | 1172242 |
| Wosid | WOS:A1975AC83500004 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |