(CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones
Kim, J; Shokova, E; Tafeenko, V; Kovalev, V
| HERO ID | 5409204 |
|---|---|
| In Press | No |
| Year | 2014 |
| Title | (CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones |
| Authors | Kim, J; Shokova, E; Tafeenko, V; Kovalev, V |
| Journal | Beilstein Journal of Organic Chemistry |
| Volume | 10 |
| Page Numbers | 2270-2278 |
| Abstract | A very simple and convenient reaction for 1,3-diketone preparation from carboxylic acids and aromatic ketones in TFAA/TfOH system is described. When the β-phenylpropionic acids were used as starting materials, they initially gave 1-indanones and then underwent further acylation with the formation of 2-(β-phenylpropionyl)-1-indanones as the main reaction products. In addition, the application of the proposed protocol allowed for the synthesis of selected polysubstituted pyrazoles in a one-pot procedure directly from acids and ketones. |
| Doi | 10.3762/bjoc.10.236 |
| Pmid | 25298794 |
| Wosid | WOS:000342172400001 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Claisen condensation; 1,3-diketones; heterocycles; triflic acid; trifluoroacetic acid anhydride |