Metal-Free Synthesis of Fully Substituted Pyridines via Ring Construction Based on the Domino Reactions of Enaminones and Aldehydes
Wan, JP; Jing, Y; Hu, C; Sheng, S
| HERO ID | 5415155 |
|---|---|
| In Press | No |
| Year | 2016 |
| Title | Metal-Free Synthesis of Fully Substituted Pyridines via Ring Construction Based on the Domino Reactions of Enaminones and Aldehydes |
| Authors | Wan, JP; Jing, Y; Hu, C; Sheng, S |
| Journal | Journal of Organic Chemistry |
| Volume | 81 |
| Issue | 15 |
| Page Numbers | 6826-6831 |
| Abstract | An unprecedented domino reaction involving primary enaminones/enaminoesters and aldehydes has been developed for the synthesis of fully substituted pyridines. The construction of the products has been accomplished via the cascade generation of two C-C and one C-N bond by simply using TfOH as a promoter. |
| Doi | 10.1021/acs.joc.6b01149 |
| Pmid | 27367181 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |