Triflic acid-promoted cycloisomerization of 2-alkynylphenyl isothiocyanates and isocyanates: a novel synthetic method for a variety of indole derivatives
Saito, T; Sonoki, Y; Otani, T; Kutsumura, N
| HERO ID | 5415992 |
|---|---|
| In Press | No |
| Year | 2014 |
| Title | Triflic acid-promoted cycloisomerization of 2-alkynylphenyl isothiocyanates and isocyanates: a novel synthetic method for a variety of indole derivatives |
| Authors | Saito, T; Sonoki, Y; Otani, T; Kutsumura, N |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 12 |
| Issue | 42 |
| Page Numbers | 8398-8407 |
| Abstract | A new approach towards the synthesis of indole derivatives via triflic acid-promoted cycloisomerization with rearrangement of 2-(alkyn-1-yl)phenyl isothiocyanates and 2-(alkyn-1-yl)phenyl isocyanates has been achieved. By this methodology, structurally diverse types of indole derivatives such as thieno- and furo-indoles, spiro-indolethiones, spiro-oxindoles, and 3-alkylidene-oxindoles were synthesized. |
| Doi | 10.1039/c4ob00825a |
| Pmid | 25008251 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |