A convenient method for the conversion of N-acyloxazolidinones to hydroxamic acids
Sibi, MP; Hasegawa, H; Ghorpade, SR
| HERO ID | 5417749 |
|---|---|
| In Press | No |
| Year | 2002 |
| Title | A convenient method for the conversion of N-acyloxazolidinones to hydroxamic acids |
| Authors | Sibi, MP; Hasegawa, H; Ghorpade, SR |
| Journal | Organic Letters |
| Volume | 4 |
| Issue | 20 |
| Page Numbers | 3343-3346 |
| Abstract | Treatment of N-acyloxazolidinones with hydroxylamines using samarium triflate as a Lewis acid provides the corresponding hydroxamic acids in 50-98% yields at room temperature. The conversion proceeds with high degree of chemoselectivity and without racemization of chiral centers alpha- to the acyl group. [reaction: see text] |
| Doi | 10.1021/ol0263301 |
| Pmid | 12323014 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |