Synthesis of aryl-2-deoxy-d-lyxo/arabino-hexopyranosides from 2-deoxy-1-thioglycosides

Paul, S; Jayaraman, N

HERO ID

579180

Reference Type

Journal Article

Year

2007

Language

English

PMID

17477910

HERO ID 579180
In Press No
Year 2007
Title Synthesis of aryl-2-deoxy-d-lyxo/arabino-hexopyranosides from 2-deoxy-1-thioglycosides
Authors Paul, S; Jayaraman, N
Journal Carbohydrate Research
Volume 342
Issue 10
Page Numbers 1305-1314
Abstract The synthesis of either anomers of aryl 2-deoxy-d-glycopyranosides from 2-deoxy-1-thioglycosides is reported. The [alpha]-anomers form as the major product when thioglycosides react with differently substituted phenols and naphthols, in the presence of N-iodosuccinimide/triflic acid. On the other hand, reaction of the thioglycosides with bromine initially, followed by reaction with aryloxy anions lead to aryl 2-deoxy-[beta]-d-glycosides with high specificities.
Doi 10.1016/j.carres.2007.02.030
Pmid 17477910
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Aryl glycosides; Deoxysugars; Glycosylations; Thioglycosides
Is Qa No