Mutagenicity of volatile organic compounds commonly found as contaminants in potable water supplies
Calandra, TD; Caruso, JE; Shahied, SI
HERO ID
628823
Reference Type
Journal Article
Year
1987
Language
English
| HERO ID | 628823 |
|---|---|
| In Press | No |
| Year | 1987 |
| Title | Mutagenicity of volatile organic compounds commonly found as contaminants in potable water supplies |
| Authors | Calandra, TD; Caruso, JE; Shahied, SI |
| Journal | Environmental Mutagenesis |
| Volume | 9 |
| Issue | Suppl 8 |
| Page Numbers | 22 |
| Abstract | The mutagenicity of the volatile organic chemicals most commonly found as contaminants in New Jersey potable water supplies has been evaluated using the Ames Salmonella/mammalian microsome preincubation assay protocol. Trichloroethylene, tetrachloroethylene, 1,1,1-trichloroethane, methylene chloride, trans-1,2-dichloroethylene, carbon tetrachloride, benzene and 1,2-dichloroethane were investigated using the TA 97a, TA 98, TA 100 and TA 102 strains of Salmonella typhimurium. The mutagenicity of each compound acting singly and in concert with each of the other substances studied was tested. No mutagenicity was observed for benzene, trichloroethylene or trans-1,2-dichloroethylene. Methylene chloride was found to be mutagenic to TA 98 and induced mutagenesis above the background level in TA 102. 1,2-dichloroethane appeared to be slightly mutagenic to TA 100 and more so with TA 102. Preliminary results indicated that tetrachloroethylene, carbon tetrachloride and 1,1,1-trichloroethane may induce mutagenesis in TA 97a. Data comparing the mutagenicity of these substances when acting in pairs will be compared with that obtained when acting alone. |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: EIGHTEENTH ANNUAL MEETING OF THE ENVIRONMENTAL MUTAGEN SOCIETY ISSN: |
| Is Public | Yes |
| Language Text | English |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>General Biology-Symposia</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Cytology and Cytochemistry-Animal</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Genetics and Cytogenetics-Animal</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Biochemical Studies-General</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Toxicology-Environmental and Industrial Toxicology</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Physiology and Biochemistry of Bacteria</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Genetics of Bacteria and Viruses</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Microbiological Apparatus</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Public Health: Environmental Health-Air</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>Enterobacteriaceae (1979- )</kw> |
| Is Qa | No |