Teratological assessment of Trinitro - RDX in rats
Angerhofer, R; Davis, G; Balezewski, L
HERO ID
630059
Reference Type
Technical Report
Year
1986
Language
English
| HERO ID | 630059 |
|---|---|
| Year | 1986 |
| Title | Teratological assessment of Trinitro - RDX in rats |
| Authors | Angerhofer, R; Davis, G; Balezewski, L |
| Publisher Text | U.S. Army Environmental Hygiene Agency |
| City | Aberdeen Proving Ground, MD |
| Page Numbers | 24 |
| Abstract | A teratology study in rats was performed to define the effects of trinitro-RDX on the developing fetus, oral dosage levels of 2, 6, and 20 mg rat/kg/day were administered to pregnant female rats critical period of organogenesis. Fetuses derived from RDX-treated dams had significantly lower body weights and lengths when compared to control fetuses. It was recommended that human females of childbearing age be protected from exposure to trinitro-RDX by means of appropriate industrial hygiene practices. It was further recommended that additional developmental toxicity studies be performed. |
| Report Number | 75-51-0573-86 |
| Ntis Number | ADA166249 |
| Url | http://www.dtic.mil/dtic/tr/fulltext/u2/a166249.pdf |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | RATS, TOXICITY, RDX, FETUS, HUMANS, LENGTH, LEVEL(QUANTITY), BODY WEIGHT, FEMALES, INDUSTRIAL HYGIENE, ORAL DOSAGE, NITRO RADICALS, Teratology |
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