Mutagenicity of polynitroaromatic explosives in microbial test systems
Whong, WZ; Speciner, ND; Edwards, GS
HERO ID
630142
Reference Type
Journal Article
Year
1980
Language
English
| HERO ID | 630142 |
|---|---|
| In Press | No |
| Year | 1980 |
| Title | Mutagenicity of polynitroaromatic explosives in microbial test systems |
| Authors | Whong, WZ; Speciner, ND; Edwards, GS |
| Journal | Proceedings. Annual Meeting of the American Association for Cancer Research |
| Volume | 21 |
| Issue | MAR |
| Page Numbers | 195 |
| Abstract | Of nine nitroaromatic explosives tested, seven have moderate to strong mutagenic activity. Included in this group is 2,4,6-trinitrotoluene (TNT), the most widely used military explosive. Most of these compounds act as direct-acting, frameshift mutagens in the Ames Salmonella test system. An exception is tetryl (N,2,4,6-tetranitro-N-methylaniline) a military booster explosive. While this compound is also a direct acting mutagen (in Salmonella, Saccharomyces and Neurospora) it causes only base-pair substitution mutations. |
| Is Certified Translation | No |
| Dupe Override | 630142 |
| Comments | Journal: 71ST ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ISSN: |
| Is Public | Yes |
| Language Text | English |
| Is Qa | No |