[Estimation of daily oral exposure to phthalates derived from soft polyvinyl chloride baby toys]

Sugita, T; Kawamura, Y; Tanimura, M; Matsuda, R; Niino, T; Ishibashi, T; Hirabahashi, N; Matsuki, Y; Yamada, T; Maitani, T

HERO ID

680152

Reference Type

Journal Article

Year

2003

Language

Japanese

PMID

12846156

HERO ID 680152
In Press No
Year 2003
Title [Estimation of daily oral exposure to phthalates derived from soft polyvinyl chloride baby toys]
Authors Sugita, T; Kawamura, Y; Tanimura, M; Matsuda, R; Niino, T; Ishibashi, T; Hirabahashi, N; Matsuki, Y; Yamada, T; Maitani, T
Journal Shokuhin Eiseigaku Zasshi / Journal of the Food Hygienic Society of Japan
Volume 44
Issue 2
Page Numbers 96-102
Abstract Daily oral exposure of babies to phthalate was estimated on the basis of the mouthing time of infants and the oral concentration of diisononyl phthalate (DINP) released from polyvinyl chloride (PVC) toy specimens. Total mouthing time, including the use of pacifiers, ranged widely from 11.4 min to 351.8 min with the mean of 105.3 +/- 72.1 min. The mean of the total mouthing time without pacifiers was 73.9 +/- 32.9 min. The average amount of DINP in saliva was 92.4 +/- 56.8 micrograms/10 cm2/hr, ranging from 13.2 micrograms/10 cm2/hr to 240.4 micrograms/10 cm2/hr. The exposure of phthalate in two different trials was estimated by the method of Monte Carlo simulation, one with the total mouthing time with pacifiers and the other with the total mouthing time without pacifiers. The average exposure in the former trial was 21.4 micrograms/kg/day and the 95th percentile was 65.8 micrograms/kg/day, while in the latter it was 14.8 micrograms/kg/day and the 95th percentile was 35.7 micrograms/kg/day.
Doi 10.3358/shokueishi.44.96
Pmid 12846156
Wosid WOS:000182534300004
Url <Go to ISI>://CCC:000182534300004
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000182534300004
Is Public Yes
Language Text Japanese
Keyword Humans; Infant; Pacifiers; Play and Playthings; Polyvinyl Chloride/ analysis; Sucking Behavior/physiology; Time Factors
Is Qa No