Deposition of monodisperse insoluble aerosol particles in the 0.005 to 0.2 μm size range within the human respiratory tract

Schiller, CF; Gebhart, J; Heyder, J; Rudolf, G; Stahlhofen, W

HERO ID

6945

Reference Type

Journal Article

Year

1988

Language

English

HERO ID 6945
In Press No
Year 1988
Title Deposition of monodisperse insoluble aerosol particles in the 0.005 to 0.2 μm size range within the human respiratory tract
Authors Schiller, CF; Gebhart, J; Heyder, J; Rudolf, G; Stahlhofen, W
Journal Annals of Occupational Hygiene
Volume 32
Issue inhaled_particles_VI
Page Numbers 41-49
Abstract In 4 subjects with normal lung function total deposition of monodisperse, hydrophobic, uncharged silver particles in the 0.005 to 0.08 μm size range was investigated for a variety of breathing patterns during steady state mouth- and nose breathing. The evaluation of deposition was based upon measurements of mean particle number concentration in inspired and expired air by means of a condensation nucleus counter. Owing to the diffusional particle transport, total deposition increases with decreasing particle size and increasing mean residence time of the aerosol in the lungs. With decreasing particle size the time dependence becomes less and the effect of tidal volume more significant. A semi-empirical formula is derived which fits the experimental data.
Doi 10.1093/annhyg/32.inhaled_particles_VI.41
Url https://www.sciencedirect.com/science/article/abs/pii/B9780080341859500103
Is Certified Translation No
Dupe Override No
Conference Location Cambridge, United Kingdom
Conference Name International Symposium and Workshop on Lung Dosimetry
Conference Date September 2-6, 1985
Is Public Yes
Language Text English