Determination of phthalates in diet and bedding for experimental animals using gas chromatography-mass spectrometry

Kondo, F; Okumura, M; Oka, H; Nakazawa, H; Izumi, S; Makino, T

HERO ID

697398

Reference Type

Journal Article

Year

2010

Language

English

PMID

19949769

HERO ID 697398
In Press No
Year 2010
Title Determination of phthalates in diet and bedding for experimental animals using gas chromatography-mass spectrometry
Authors Kondo, F; Okumura, M; Oka, H; Nakazawa, H; Izumi, S; Makino, T
Journal Bulletin of Environmental Contamination and Toxicology
Volume 84
Issue 2
Page Numbers 212-216
Abstract We have developed a gas chromatography-mass spectrometry method to measure five phthalates (dibutyl phthalate, butylbenzyl phthalate, di-2-ethylhexyl phthalate, diisooctyl phthalate, and diisononyl phthalate) in diets and beddings for experimental animals. The recoveries from diets and beddings spiked with five phthalates were 98.8%-148% with coefficients of variation of 0.4%-7.8% for diets and 94.7%-146% with coefficients of variation of 1.0%-5.0% for beddings. We analyzed commercial animal diets and beddings, and found that the levels of phthalates varied from sample to sample; the concentrations of five phthalates were 141-1,410 ng/g for diets and 20.5-7,560 ng/g for beddings.
Doi 10.1007/s00128-009-9919-x
Pmid 19949769
Wosid WOS:000273846500013
Url https://search.proquest.com/docview/744611465?accountid=171501
Is Certified Translation No
Dupe Override No
Is Public Yes
Language Text English
Keyword Air/analysis; Air Pollutants/analysis; Animal Feed/ analysis; Animals; Animals, Laboratory; Calibration; Diet; Food Contamination; Gas Chromatography-Mass Spectrometry; Phthalic Acids/ analysis; Reference Standards; Rodentia; Water/analysis; Water Pollutants/analysis
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