The relationship between ambient particulate matter and respiratory mortality: A multi-city study in Italy

Faustini, A; Stafoggia, M; Berti, G; Bisanti, L; Chiusolo, M; Cernigliaro, A; Mallone, S; Primerano, R; Scarnato, C; Simonato, L; Vigotti, MA; Forastiere, F

HERO ID

699138

Reference Type

Journal Article

Year

2011

Language

English

PMID

21233266

HERO ID 699138
In Press No
Year 2011
Title The relationship between ambient particulate matter and respiratory mortality: A multi-city study in Italy
Authors Faustini, A; Stafoggia, M; Berti, G; Bisanti, L; Chiusolo, M; Cernigliaro, A; Mallone, S; Primerano, R; Scarnato, C; Simonato, L; Vigotti, MA; Forastiere, F
Journal European Respiratory Journal
Volume 38
Issue 3
Page Numbers 538-547
Abstract The association of air pollutants with natural and respiratory mortality has been consistently reported. However, several aspects of the relationship between particles with an aerodynamic diameter of less than 10 micrometers (PM10) and respiratory mortality require further investigation. To assess the PM10 - respiratory mortality association in Italy and to examine potentially susceptible groups. All natural (n. 276,205) and respiratory deaths (n. 19,629) occurring among 35-plus-year-olds in ten northern, central and southern Italian cities in 2001-2005 were selected. Data for 10-micron particulate matter, nitrogen dioxide and ozone were obtained. A time-stratified case-crossover analysis was carried out. Different cumulative lags were selected to analyse immediate, delayed, prolonged and best-time effects of air pollution. The shape of the exposure-response relationship was analysed. Age, gender, chronic conditions and death site were investigated as potential effect modifiers. We found a 2.29% (IC95%=1.03; 3.58) increase in respiratory mortality at 0-3 lags. The increase in respiratory mortality was higher in summer (7.57%). The exposure-response curve had a linear shape without any threshold. Gender and chronic diseases modified the relationship between particulate matter and respiratory mortality. The effect of particulate on respiratory mortality was stronger and more persistent than that on natural mortality. Females and chronic disease sufferers were more likely to die of a respiratory disease caused by air pollution than males and healthy people.
Doi 10.1183/09031936.00093710
Pmid 21233266
Wosid WOS:000294458300012
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000294458300012
Is Public Yes
Language Text English
Keyword Case-crossover design; multi-city study; particulate matter; respiratory mortality
Is Qa No
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