Ambient temperature, air pollution, and heart rate variability in an aging population

Ren, C; Park, S; O'Neill, M; Sparrow, D; Vokonas, P; Schwartz, J

HERO ID

699417

Reference Type

Journal Article

Year

2011

Language

English

PMID

21385834

HERO ID 699417
In Press No
Year 2011
Title Ambient temperature, air pollution, and heart rate variability in an aging population
Authors Ren, C; Park, S; O'Neill, M; Sparrow, D; Vokonas, P; Schwartz, J
Journal American Journal of Epidemiology
Volume 173
Issue 9
Page Numbers 1013-1021
Abstract Studies show that ambient temperature and air pollution are associated with cardiovascular disease and that they may interact to affect cardiovascular events. However, few epidemiologic studies have examined mechanisms through which ambient temperature may influence cardiovascular function. The authors examined whether temperature was associated with heart rate variability (HRV) in a Boston, Massachusetts, study population and whether such associations were modified by ambient air pollution concentrations. The population was a cohort of 694 older men examined between 2000 and 2008. The authors fitted a mixed model to examine associations between temperature and air pollution and their interactions with repeated HRV measurements, adjusting for covariates selected a priori on the basis of their previous studies. Results showed that higher ambient temperature was associated with decreases in HRV measures (standard deviation of normal-to-normal intervals, low-frequency power, and high-frequency power) during the warm season but not during the cold season. These warm-season associations were significantly greater when ambient ozone levels were higher (>22.3 ppb) but did not differ according to levels of ambient fine (≤2.5 μm) particulate matter. The authors conclude that temperature and ozone, exposures to both of which are expected to increase with climate change, might act together to worsen cardiovascular health and/or precipitate cardiovascular events via autonomic nervous system dysfunction.
Doi 10.1093/aje/kwq477
Pmid 21385834
Wosid WOS:000290046900008
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000290046900008
Is Public Yes
Language Text English
Keyword air pollution; heart rate; interaction; ozone; particulate matter; temperature
Is Qa No