Toxicology study no. 87-XE-059F-06: Biomarkers of RDX exposure in breath of swine, August - September 2006
Bannon, DI
| HERO ID | 699418 |
|---|---|
| Year | 2006 |
| Title | Toxicology study no. 87-XE-059F-06: Biomarkers of RDX exposure in breath of swine, August - September 2006 |
| Authors | Bannon, DI |
| Publisher Text | U.S. Army Center for Health Promotion and Preventive Medicine |
| City | Aberdeen Proving Ground, MD |
| Abstract | 1. PURPOSE. This study was conducted to assess the feasibility of using exhaled breath condensate as a non-invasive sampling method for measuring biomarkers ofRDX exposure in Yorkshire pigs. A secondary objective was to assess the absorption and distribution of a single oral dose ofRDX throughout the body. 2. CONCLUSION. Breath sampling of juvenile swine was considered technically feasible for this kind of study while simultaneous sampling of blood from the ear permitted monitoring of RDX absorption over time. This model can be used again for this kind of study. 3. RECOMMENDATION. Use this model to continue studies on breath analysis of swine with modifications and more effective trapping of breath. |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |