Transport of O2 along a model pathway through the respiratory region of the lung
Davidson, MR; Fitz-Gerald, JM
HERO ID
71520
Reference Type
Journal Article
Year
1974
Language
English
PMID
| HERO ID | 71520 |
|---|---|
| In Press | No |
| Year | 1974 |
| Title | Transport of O2 along a model pathway through the respiratory region of the lung |
| Authors | Davidson, MR; Fitz-Gerald, JM |
| Journal | Bulletin of Mathematical Biology |
| Volume | 36 |
| Issue | 3 |
| Page Numbers | 275-303 |
| Abstract | A pathway through the system of branching in the respiratory region of the lung is modelled by a circular cylinder, closed at one end, with partitions which define the component respiratory units. In this model the transport of O2 during inspiration, generated by diffusion is compared with that produced by diffusion together with convection and the importance of convection in the respiratory region in promoting oxygen uptake at the alveolar wall is discussed. For this discussion it is only necessary to consider inspiration. The equations are solved numerically for flow rates of 10, 85 and 200 liters/min. O2 uptake at the wall and curves of constant O2 concentration are shown to illustrate the influence of convection. It is found that after a 2 sec inspiration from an O2 tension of 98 mm Hg and a lung volume of 2300 ml, convection is about 12 per cent as important as diffusion at a flow rate of 85 liters/min, whereas at 10 liters/min convection is only about 0.4 per cent as important as diffusion. |
| Doi | 10.1007/BF02461329 |
| Pmid | 4424249 |
| Wosid | WOS:A1974U391400005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |