The Yugoslavia Prospective Lead Study: Contributions of prenatal and postnatal lead exposure to early intelligence

Wasserman, GA; Liu, X; Popovac, D; Factor-Litvak, P; Kline, J; Waternaux, C; Loiacono, N; Graziano, JH

HERO ID

73023

Reference Type

Journal Article

Year

2000

Language

English

PMID

11120386

HERO ID 73023
In Press No
Year 2000
Title The Yugoslavia Prospective Lead Study: Contributions of prenatal and postnatal lead exposure to early intelligence
Authors Wasserman, GA; Liu, X; Popovac, D; Factor-Litvak, P; Kline, J; Waternaux, C; Loiacono, N; Graziano, JH
Journal Neurotoxicology and Teratology
Volume 22
Issue 6
Page Numbers 811-818
Abstract To investigate associations between the timing of lead (Pb) exposure on early intelligence, we examined the results of psychometric evaluations at ages 3, 4, 5, and 7 years, from 442 children whose mothers were recruited during pregnancy from a smelter town and a non-lead-exposed town in Yugoslavia. We compared the relative contribution of prenatal blood lead (BPb) with that of relative increases in BPb in either the early (0û2 years) or the later (from 2 years on) postnatal period to child intelligence measured longitudinally at ages 3 and 4 (McCarthy GCI), 5 (Wechsler Preschool and Primary Scale of Intelligence-Revised, WPPSI-R IQ), and 7 (Wechsler Intelligence Scale for Children-version III, WISC-III IQ), controlling for: Home Observation for Measurement of the Environment (HOME) quality; maternal age, intelligence, education, and ethnicity; and birthweight and gender. Elevations in both prenatal and postnatal BPb were associated with small decrements in young children's intelligence.
Doi 10.1016/S0892-0362(00)00106-9
Pmid 11120386
Wosid WOS:000166006500003
Url https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033674438&doi=10.1016%2fS0892-0362%2800%2900106-9&partnerID=40&md5=1ccf61ad6edfb701be795004e6423eae
Is Certified Translation No
Dupe Override No
Comments Scopus URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033674438&doi=10.1016%2fS0892-0362%2800%2900106-9&partnerID=40&md5=1ccf61ad6edfb701be795004e6423eae
Is Public Yes
Language Text English
Keyword Lead exposure; Children; Longitudinal; Intelligence
Is Peer Review No
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